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C-008

Supelco

Cocaine solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C17H21NO4
CAS Number:
50-36-2
Molecular Weight:
303.35
MDL number:
MFCD00056906
UNSPSC Code:
41116107
PubChem Substance ID:
329774761
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3

InChI

1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1

InChI key

ZPUCINDJVBIVPJ-LJISPDSOSA-N

General description

A Certified Spiking Solution® suitable for use in LC/MS or GC/MS testing applications for forensic analysis, urine drug testing, or clinical toxicology. Cocaine is a tropane alkaloid and illicit drug obtained from the leaves of the coca plant. This popular recreational drug is a powerful stimulant of the central nervous system with appetite suppressant and topical anesthetic properties.

Application


  • High-purity cocaine hydrochloride for scientific research: An innovative analytical method was developed using magnetic nanoparticles for the forensic detection of cocaine and its metabolites in postmortem blood samples, underlining its precision in detecting and quantifying cocaine in complex biological matrices (de Souza Schwarz et al., 2024).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Watchareewan Thongsaard et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96 Suppl 1, S85-S89 (2013-06-04)
Thunbergia laurifolia Linn. (TL) is a herbal medicine used as an antidote for several poisonous agents in Thai traditional medicine. TL were reported not only to significantly increase potassium-stimulated dopamine release from rat striatal slices but also potentiated the effect
Risheng Xu et al.
Neuron, 78(4), 623-630 (2013-05-31)
Cocaine's behavioral-stimulant effects derive from potentiation of synaptic signaling by dopamine and serotonin leading to transcriptional alterations in postsynaptic cells. We report that a signaling cascade involving nitric oxide (NO) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mediates cocaine's transcriptional and behavioral actions.
Carlos Manuel Lima Reis da Silva et al.
Journal of psychoactive drugs, 45(2), 195-198 (2013-08-03)
The topic of ophthalmic use of cocaine in clinical practice has a long history; nevertheless, the possible influence and pathways of action of inhaled cocaine in the human eye remain unknown. This study evaluates the effect of snorted cocaine in
Coca science seeks an answer in kilos.
Antonio Regalado
Science (New York, N.Y.), 341(6145), 453-453 (2013-08-03)
W Pitchot et al.
Revue medicale de Liege, 68(5-6), 294-297 (2013-07-31)
Cocaine is the second most commonly used illicit drug after cannabis in the general population. Cocaine is a powerful stimulating agent of the central nervous system and a highly addictogenic drug. Somatic and psychiatric consequences of cocaine addiction are major
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