H-017

m-Hydroxybenzoylecgonine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₆H₁₉NO₅
• CAS Number: 129944-99-6
• Molecular Weight: 305.33
• MDL number: MFCD00274048
• UNSPSC Code: 41116107
• PubChem Substance ID: 329815107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland)
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)c3cccc(O)c3)C(O)=O
• InChI: 1S/C16H19NO5/c1-17-10-5-6-12(17)14(15(19)20)13(8-10)22-16(21)9-3-2-4-11(18)7-9/h2-4,7,10,12-14,18H,5-6,8H2,1H3,(H,19,20)/t10-,12+,13-,14+/m0/s1
• InChI key: XCJJCRPRQYXLRE-AHLTXXRQSA-N

Description

General description

m-Hydroxybenzoylecgonine is a urinary metabolite of cocaine and a biomarker for determination of cocaine use. This Certified Spiking Solution^® is applicable to use in urine drug testing, clinical toxicology, or forensic analysis by LC-MS/MS or GC/MS.

Application

• m-Hydroxybenzoylecgonine as a forensic toxicology standard: A study optimized and validated a method for analyzing cocaine and several metabolites including m-Hydroxybenzoylecgonine in human urine via gas chromatography-mass spectrometry, emphasizing its utility in forensic and toxicological applications (Fernández et al., 2019).


• m-Hydroxybenzoylecgonine for stability studies in toxicology: Research assessed the stability of cocaine metabolites such as m-Hydroxybenzoylecgonine in meconium, contributing to better forensic practices by determining optimal storage conditions (Wu et al., 2017).


• Accelerated solvent extraction featuring m-Hydroxybenzoylecgonine: A protocol was developed for the extraction of cocaine and its biomarkers from meconium, utilizing m-Hydroxybenzoylecgonine to monitor drug exposure, enhancing the accuracy of drug testing in neonatal care (Mantovani et al., 2014).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup