RES0704P-A7

PIPES, disodium salt

• Synonym(s): PIPES disodium salt, 1,4-Piperazinediethanesulfonic acid disodium salt, Piperazine-1,4-bis(2-ethanesulfonic acid) disodium salt
• Empirical Formula (Hill Notation): C₈H₁₆N₂Na₂O₆S₂
• CAS Number: 76836-02-7
• Molecular Weight: 346.33
• Beilstein: 9453872
• EC Number: 278-562-3
• MDL number: MFCD00064349
• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin and microbial; tested
• useful pH range: 6.1-7.5
• pKa (25 °C): 6.8
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: [Na+].[Na+].[O-]S(=O)(=O)CCN1CCN(CC1)CCS([O-])(=O)=O
• InChI: 1S/C8H18N2O6S2.2Na/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16;;/h1-8H2,(H,11,12,13)(H,14,15,16);;/q;2*+1/p-2
• InChI key: GMHSTJRPSVFLMT-UHFFFAOYSA-L

Description

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

PIPES Disodium is the sodium salt form of PIPES and is a biological buffer often referred to as a “Good′s” buffer. The pKa of PIPES is 6.8 which makes it ideal for biological applications at physiological conditions. PIPES Disodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

PIPES Disodium can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for cell culture and diagnostic reagent production.

Packaging

Product is available in the following package sizes:
RES0704P-A701X: 100 gm container
RES0704P-A702X: 1 kg container
RES0704P-A704X: 10 kg container

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable