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T-093

Supelco

Delta9-Tetrahydrocannabinolic acid A solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

THCA-A

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About This Item

Empirical Formula (Hill Notation):
C22H30O4
CAS Number:
Molecular Weight:
358.47
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

cannabis testing
cannabis testing

format

single component solution

shipped in

dry ice

storage temp.

−70°C

SMILES string

OC1=C(C(O)=O)C(CCCCC)=CC2=C1[C@H](C=C(C)CC3)[C@@H]3C(C)(C)O2

InChI

1S/C22H30O4/c1-5-6-7-8-14-12-17-19(20(23)18(14)21(24)25)15-11-13(2)9-10-16(15)22(3,4)26-17/h11-12,15-16,23H,5-10H2,1-4H3,(H,24,25)/t15-,16-/m1/s1

InChI key

UCONUSSAWGCZMV-HZPDHXFCSA-N

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General description

This certified Snap-N-Spike® solution is suitable for THCA-A testing methods by GC/MS, LC/MS or HPLC for applications in clinical toxicology, testing of cannabis potency or impurity profiling, pharmaceutical research, forensic analysis, and urine drug testing. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.

Δ9-Tetrahydrocannabinolic acid A (THCA-A) is a non-psychoactive acidic cannabinoid found in Cannabis that reportedly exhibits anti-inflammatory, neuroprotective, and anti-cancer effects. It is also the precursor to the main psychoactive cannabinoid found in cannabis, called Δ-9-tetrahydrocannabinol (Δ-9-THC).

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Gas chromatographic-mass spectrometric (GC-MS) analysis of ten main cannabinoids from hemp inflorescences following their silylation and esterification for derivatization
  • Development and validation of an HPLC-DAD method for the simultaneous analysis of five major neutral and acidic cannabinoids in cannabis and hashish samples
  • Multi-analysis of 11 cannabinoids in biomass and extracts of different cannabis varieties by an HPLC-UV method, following the International Conference on Harmonization (ICH) Tripartite Guideline for Validation of Analytical Procedures
  • Analysis of hemp seed oil samples for identification and estimation of seven major cannabinoids by HPLC coupled to a UV detector
  • Estimation of ∆9-tetrahydrocannabinolic acid in blood and plasma samples using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • Simultaneous analysis of ∆9-tetrahydrocannabinol, ∆9-tetrahydrocannabinolic acid-A, cannabidiol, and cannabinol by an HPLC-DAD method in confiscated cannabis products

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve 14 structurally-similar cannabinoids, in under seven minutes, with excellent peak shape.

Tetrahydrocannabinolic acid A solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material.

The cannabinoids found in the Cannabis plant commonly referred to as marijuana, have grown in popularity for treating a variety of ailments from arthritis, glaucoma, and chronic pain to malnutrition, multiple sclerosis, and cancer.

Protocols

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve 14 structurally-similar cannabinoids, in under seven minutes, with excellent peak shape.

Tetrahydrocannabinolic acid A solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Cannabichromenic Acid (CBCA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL

HPLC separation of 17 important cannabinoids including CBD, delta 9 THC and THCA. Read the application note

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