S-002

Secobarbital solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₂H₁₈N₂O₃
• CAS Number: 76-73-3
• Molecular Weight: 238.28
• MDL number: MFCD00056088
• UNSPSC Code: 41116107

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• concentration: 1 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: CCCC(C)C1(CC=C)C(=O)NC(=O)NC1=O
• InChI: 1S/C12H18N2O3/c1-4-6-8(3)12(7-5-2)9(15)13-11(17)14-10(12)16/h5,8H,2,4,6-7H2,1,3H3,(H2,13,14,15,16,17)
• InChI key: KQPKPCNLIDLUMF-UHFFFAOYSA-N
• Gene Information: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Description

General description

Secobarbital, sold under the trade name Seconal^®, is a barbiturate approved for treatment of epilepsy as well as temporary treatment of insomnia. The drug is also used as a preoperative anesthetic in short surgical, diagnostic or therapeutic procedures. This Certified Spiking Solution^® is suitable for numerous GC/MS or LC/MS testing applications from clinical toxicology to urine drug testing and forensic analysis.

Application

• Barbiturate assay standardization: A research article presents a comprehensive protocol for high-throughput quantitative LC-MS/MS analysis of barbiturates, including Secobarbital, in human urine. This study is pivotal for clinical toxicology and forensic analysis, supporting accurate and efficient barbiturate detection (Gqamana and Zhang, 2024).



• Development of analytical techniques for Secobarbital: Another study details the specific analysis of Secobarbital in urine using LC-MS/MS. This research enhances the understanding of barbiturate metabolism and excretion, critical for both clinical and research settings (Campbell et al., 2024).

Recommended products

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Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Seconal is a registered trademark of Marathon Pharmaceuticals, LLC

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H301 + H311 + H331 - H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup