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About This Item
Empirical Formula (Hill Notation):
CsF
CAS Number:
Molecular Weight:
151.90
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.22
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Assay
99%
form
liquid
mp
682 °C (lit.)
density
4.115 g/mL at 25 °C (lit.)
SMILES string
[F-].[Cs+]
InChI
1S/Cs.FH/h;1H/q+1;/p-1
InChI key
XJHCXCQVJFPJIK-UHFFFAOYSA-M
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General description
Cesium fluoride is an inorganic compound known to be a source of fluoride ion and a catalyst in organic synthesis. It has been used in many organic reactions like 1,4−elimination, desilylation, transesterification, acylation, nucleophilic aromatic substitution, etherification, cross−coupling reactions and so on.
Application
Cesium fluoride can be used as:
- A base in the Suzuki cross-coupling synthesis of ortho-substituted biaryls.
- A reagent for the nucleophilic fluorination of primary halides and sulfonates in protic media such as tert-butyl and tert-pentyl alcohols.
Reactant for:
- Preparation of building blocks for synthesis of fluoroallylic compounds
- Synthesis of alcohols via hydrolysis of alkyl silyl ethers at neutral pH in buffered mixed organic-aqueous solutions
- Nucleophilic fluorination of alkynyliodonium salts to form fluorovinylic compounds
- Nucleophilic aromatic substitution (SNAr) reactions
Used in the successful synthesis of a single-crystal Dion-Jacobson phase, CsLaTa2O7, that has applications in photocatalysis and superconductivity.
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - STOT RE 2
Target Organs
Kidney,Adrenal gland
Supplementary Hazards
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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