SCP0093
Caspase Inhibitor
≥95% (HPLC)
Sinónimos:
Ac-LETD-CHO, caspase 8 inhibitor, caspase 9 inhibitor
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Fórmula empírica (notación de Hill):
C21H34N4O10
Peso molecular:
502.52
UNSPSC Code:
12352200
NACRES:
NA.32
Productos recomendados
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥80%
storage condition
protect from light
storage temp.
−20°C
Gene Information
human ... CASP8(841) , CASP9(842)
Amino Acid Sequence
Ac-Leu-Glu-Thr-Asp-al
Application
Caspase inhibitor Ac-LETD-CHO has been used to inhibit caspase-8.
Biochem/physiol Actions
The peptide Ac-Leu-Glu-Thr-Asp-al, or Ac-LETD-CHO, is a known caspase inhibitor. Ac-LETD-CHO has been reported to exert inhibitory effects on caspase 8 and on caspase 9.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Enteric glial cells counteract Clostridium difficile Toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways
Lara M
Scientific Reports (2017)
Apoptotic Regulation of Caspase Activity
Martinova, E.A., et al.
Russian J. Bioorg. Chem., 29, 471-495 (2003)
Preventive Effects of Food Components on Caspase-8-Mediated Apoptosis Induced by Dietary Carcinogen, Trp-P-1, in Rat Mononuclear Cells
Hashimoto, T., et al.
ACS Symp. Ser., 851, 128-140 (2003)
Jie Shi et al.
Biochemical pharmacology, 75(9), 1729-1742 (2008-04-02)
Indirubin-3'-monoxime (I3M) is a derivative of indirubin, an active component from a Chinese medicinal recipe with known anti-cancer function. I3M has been well established as a cyclin-dependent kinase (CDK) inhibitor, while the molecular mechanism underlying I3M-induced apoptosis has not been
Takashi Araki et al.
Nephron. Experimental nephrology, 93(3), e117-e124 (2003-03-28)
Programmed cell death is a mechanism by which organisms dispose of unwanted cells, and it is thought to be an important process in organogenesis. We have already reported the role of caspase-3 in the developing metanephros. While caspase-3 is thought
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico