SAB4504690

Anti-phospho-Bax (pSer¹⁸⁴) antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 21 kDa
• species reactivity: mouse, rat, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100
• NCBI accession no.: Q07812
• UniProt accession no.: Q07812
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer184)
• Gene Information: human ... BAX(581)

Descripción

General description

Bif-1 (BAX-interacting factor 1), a membrane-curvature inducing protein is located on human chromosome 19q13. Bif-1 is also known as SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1)/ Endophilin B1. It belongs to the membrane curvature-driving endophilin protein family.

Immunogen

The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.

Immunogen Range: 143-192

Biochem/physiol Actions

Bif-1 (BAX-interacting factor 1) plays a vital role in apoptosis. BAX gene may act as a negative regulator of autophagy in CRC (Colorectal cancer) development. Lack of Bif-1 affects lipid homeostasis and results in obesity followed by insulin resistance.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable