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C0985

Sigma-Aldrich

Cytidine 3′,5′-cyclic mono­phos­phate sodium salt

≥98% (HPLC)

Sinónimos:

cCMP sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C9H11N3O7PNa
Número de CAS:
54925-33-6
Peso molecular:
327.16
EC Number:
259-397-6
MDL number:
MFCD00037485
UNSPSC Code:
41106305
PubChem Substance ID:
329774833
NACRES:
NA.77

description

1 vial contains 50μmol or approximately 16mg

Quality Level

200

assay

≥98% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O

InChI

1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1

InChI key

RZAHVNCNTLFRHJ-IAIGYFSYSA-M

Biochem/physiol Actions

Produced by the hydrolysis of cytidine 5′-triphos­phate by the enzyme cytidylyl cyclase.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cytidine 5′-monophosphate disodium salt Sigma Grade, ≥99%, crystalline

Sigma-Aldrich

C1006

Cytidine 5′-monophosphate disodium salt

c-di-AMP sodium salt ≥98% (HPLC)

Sigma-Aldrich

SML1231

c-di-AMP sodium salt

Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
Ping Tai et al.
Molecular endocrinology (Baltimore, Md.), 25(5), 885-893 (2011-02-19)
Activation of the LH receptor (LHR) in Leydig cells results in the phosphorylation of ERK1/2 by cAMP-dependent and cAMP-independent pathways. Here we examine the mechanisms by which cAMP stimulates ERK1/2 phosphorylation. We show that the stimulation of steroidogenesis is not
Sameer B Shah et al.
Neurobiology of disease, 36(1), 11-25 (2009-06-06)
Microtubule-based neuronal transport pathways are impaired during the progression of Alzheimer's disease and other neurodegenerative conditions. However, mechanisms leading to defects in transport remain to be determined. We quantified morphological changes in neuronal cells following treatment with fibrils and unaggregated
Xiangang Zong et al.
The Journal of biological chemistry, 287(32), 26506-26512 (2012-06-21)
Activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated in vivo by direct binding of the second messenger cAMP. This process plays a fundamental role in the fine-tuning of HCN channel activity and is critical for the modulation of cardiac
Toshiaki Kume et al.
Neuroscience letters, 443(3), 199-203 (2008-08-12)
Dibutyryl cyclic AMP (dbcAMP) and retinoic acid (RA) have been demonstrated to be the inducers of morphological differentiation in SH-SY5Y cells, a human catecholaminergic neuroblastoma cell line. However, it remains unclear whether morphologically differentiated SH-SY5Y cells by these compounds acquire
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