SMB01348

Dihydrocortisol

≥95% (HPLC)

• Sinónimos: 5β-Pregnane-11β,17α,21-triol-3,20-dione, 11β,17,21-Trihydroxy-5β-pregnane-3,20-dione, 11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione, 5β-Dihydrocortisol
• Fórmula empírica (notación de Hill): C₂₁H₃₂O₅
• Número de CAS: 1482-50-4
• Peso molecular: 364.48
• MDL number: MFCD00070050
• UNSPSC Code: 51420000

Propiedades

• Quality Level: 200
• assay: ≥95% (HPLC)
• form: solid
• storage temp.: 2-8°C
• SMILES string: O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](CC3)CC(=O)CC4)C)[C@H](C2)O)CC1)C)C(=O)CO
• InChI: 1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-16,18,22,24,26H,3-11H2,1-2H3/t12-,14+,15+,16+,18-,19+,20+,21+/m1/s1
• InChI key: ACSFOIGNUQUIGE-AIPUTVCKSA-N

Descripción

General description

5β-Dihydrocortisol is the product of the enzyme steroid 5-beta-reductase, which catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone, testosterone, aldosterone, corticosterone, and cortisol to 5-beta-reduced metabolites. 5β-Dihydrocortisol has shown to potentiate the action of topically applied dexamethasone in raising the intraocular pressure in young rabbits.

Application

Metabolomics research

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H360FD,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1A - STOT RE 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3