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H4001

Sigma-Aldrich

Hydrocortisone

≥98% (HPLC)

Sinónimos:

11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M

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1 G
€293.00

€293.00

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1 G
€293.00

About This Item

Fórmula empírica (notación de Hill):
C21H30O5
Número de CAS:
50-23-7
Peso molecular:
362.46
Beilstein/REAXYS Number:
1354819
EC Number:
200-020-1
MDL number:
MFCD00011654
UNSPSC Code:
51111800
PubChem Substance ID:
24278466
NACRES:
NA.77

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biological source

synthetic (organic)

Quality Level

300

sterility

non-sterile

assay

≥98% (HPLC)

form

powder

mp

211-214 °C (lit.)

solubility

water: 0.28 g/L at 25 °C

application(s)

cell analysis

shipped in

ambient

storage temp.

room temp

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1 of 4

Este artículo
3867H6909386698
Hydrocortisone ≥98% (HPLC)

H4001

Hydrocortisone

Hydrocortisone Steroid hormone of the adrenal cortex with anti-inflammatory properties.

3867

Hydrocortisone

Hydrocortisone solution 50 μM, sterile-filtered, BioXtra, suitable for cell culture

H6909

Hydrocortisone solution

Hydrocortisone, Chromatographic Standard Conforms to USP Reference Standard.

386698

Hydrocortisone, Chromatographic Standard

form

powder

form

solid

form

liquid

form

solid

Quality Level

300

Quality Level

100

Quality Level

500

Quality Level

100

storage temp.

room temp

storage temp.

10-30°C

storage temp.

−20°C

storage temp.

10-30°C

solubility

water: 0.28 g/L at 25 °C

solubility

ethanol: 15 mg/mL

solubility

-

solubility

DMSO: 10 mg/mL, ethanol: soluble

shipped in

ambient

shipped in

ambient

shipped in

dry ice

shipped in

ambient

Biochem/physiol Actions

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Primary glucocorticoid secreted by the adrenal cortex.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Related product

Referencia del producto
Descripción
Precios

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Repr. 1A - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

  • Hoja de especificación

    • Elija entre una de las versiones más recientes:

    Certificados de análisis (COA)

    Lot/Batch Number
    SLCL5508
    SLCM0440
    SLCK2191
    SLCJ3971
    SLCJ0528

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    Margriet A B Veldhorst et al.
    The Journal of clinical endocrinology and metabolism, 99(1), 285-290 (2014-01-05)
    Pathologically increased cortisol exposure induces obesity, but it is not known whether relatively high cortisol within the physiological range is related to childhood obesity. The aim of the study was to compare hair cortisol concentrations between obese and normal-weight children.
    Florian Hardeveld et al.
    Psychoneuroendocrinology, 50, 62-71 (2014-09-03)
    Although HPA-axis activity has been studied extensively in relation to depression, there is no consensus whether HPA-axis parameters predicts major depressive disorder (MDD) recurrence. We investigated whether HPA-axis parameters (cortisol awakening response (CAR), the dexamethasone suppression test (DST) and evening
    K J Rademaker et al.
    Archives of disease in childhood. Fetal and neonatal edition, 93(1), F58-F63 (2007-09-13)
    The benefits versus the risks of postnatal administration of steroids in preterm-born infants are still debatable. This review examines the literature on postnatal hydrocortisone treatment for chronic lung disease (CLD) in preterm-born infants with a particular focus on the effects
    Liselotte van Bloemendaal et al.
    Diabetes, 63(12), 4186-4196 (2014-07-30)
    Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 diabetes (T2DM), improve glycemic control and stimulate satiety, leading to decreases in
    Rachel Yehuda et al.
    The American journal of psychiatry, 171(8), 872-880 (2014-05-17)
    Differential effects of maternal and paternal posttraumatic stress disorder (PTSD) have been observed in adult offspring of Holocaust survivors in both glucocorticoid receptor sensitivity and vulnerability to psychiatric disorder. The authors examined the relative influences of maternal and paternal PTSD
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