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Merck
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Key Documents

06-890

Sigma-Aldrich

Anti-HDAC3 Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human, rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_003883

UniProt accession no.

O15379

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... HDAC3(8841)

Specificity

HDAC3

Immunogen

peptide corresponding to amino acids 411-428 of human HDAC3 (NEFYDGDHDNDKESDVEI)

Application

Anti-HDAC3 Antibody is a Rabbit Polyclonal Antibody for detection of HDAC3 also known as histone deacetylase 3 & has been tested in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Quality

routinely evaluated by immunoblot on a HeLa RIPA cell lysate

Target description

49kDa

Physical form

Format: Purified
Protein A chromatography
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Referencia del producto
Descripción
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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Histone acetylation and transcriptional regulatory mechanisms.
Struhl, K
Genes & Development, 12, 599-606 (1998)
K Nakade et al.
Cell death and differentiation, 14(8), 1398-1405 (2007-04-28)
Among the events that control cellular differentiation, the acetylation of histones plays a critical role in the regulation of transcription and the modification of chromatin. Jun dimerization protein 2 (JDP2), a member of the AP-1 family, is an inhibitor of
Y Zeng et al.
The Journal of biological chemistry, 273(44), 28921-28930 (1998-10-24)
Histone deacetylase-2 (HDAC2) is a component of a complex that mediates transcriptional repression in mammalian cells. A mouse HDAC2 cDNA was used to identify several recombinant clones containing the entire mouse HDAC2 gene. The mouse HDAC2 gene spans over 36
Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression
Li, J., et al
Genes & Development, 16, 687-692 (2002)
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.
Bilodeau, S; Vallette-Kasic, S; Gauthier, Y; Figarella-Branger, D; Brue, T; Berthelet et al.
Genes & Development null
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