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Key Documents

SRP5252

Sigma-Aldrich

PKC-δ, active, GST tagged human

PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

MAY1, MGC49908, PRKCD, nPKC-delta

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO®

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

213-388 nmol/min·mg

mol wt

~104 kDa

NCBI accession no.

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PRKCD(5580)

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protein kinase C-d inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo.
Chen Z
BMC Cancer (2014)
Cancer Gene List
Ma Hongbao
Cancer Biology & Medicine (2016)
Loss of PKCd Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/?-Catenin Pathway and Mcl-1 Accumulation
M. Luz Flores
Molecular Cancer Therapeutics (2016)
Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors.
Dal Pra I
Experimental Cell Research (1999)
Identification of proteins interacting with protein kinase C-d in hyperthermia-induced apoptosis and thermotolerance of Tca8113 cells.
Liu J
Molecular Medicine Reports (2015)

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