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RDD009

Sigma-Aldrich

Trizma® hydrochloride

anhydrous, free-flowing, Redi-Dri™, ≥99.0%

Synonym(s):

TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride

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About This Item

Linear Formula:
NH2C(CH2OH)3 · HCl
CAS Number:
1185-53-1
Molecular Weight:
157.60
Beilstein:
3675235
EC Number:
214-684-5
MDL number:
MFCD00012590
UNSPSC Code:
12161700
PubChem Substance ID:
329824220
NACRES:
NA.25

grade

anhydrous

Quality Level

100

product line

Redi-Dri™

Assay

≥99.0%

form

powder

quality

free-flowing

impurities

≤0.5% water (Karl Fischer)

color

white

useful pH range

7.0-9.0

pKa (25 °C)

8.1

mp

150-152 °C

solubility

H2O: soluble, clear, colorless

absorption

≤0.05 at 290 nm at 40%

SMILES string

Cl.NC(CO)(CO)CO

InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

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Other Notes

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL5616
SLCF5653
SLCD4676
SLBX7497
SLBX2856

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Tris base =99.9% (titration), abs., 100 mg/mL, 300 nm ≤0.015

Sigma-Aldrich

TRIS-RO

Tris base

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