CHROMTH-RO
Roche
Chromozym TH
Synonym(s):
thrombin substrate
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About This Item
UNSPSC Code:
12352204
Recommended Products
Assay
90% (Tosyl-Gly-Pro-Arg-4-nitranilide acetate (enzymatic))
90% (enzymatic)
Quality Level
form
powder
mol wt
Mr 662.62
packaging
pkg of 100 mg (11585398001)
pkg of 20 mg (10206849001)
manufacturer/tradename
Roche
shipped in
ambient
storage temp.
20-25°C
General description
Chromozym® TH is a chromophoric substrate mostly used to detect thrombin activity†
Tosyl-Gly-Pro-Arg-4-nitranilide acetate
Application
Use Chromozym® TH as a substrate for the determination of serine proteases, specifically thrombin in aqueous solutions.
Quality
Contaminant: 1% free 4-nitraniline
Sequence
Tosyl-glycyl-polyl-arginine-4-nitranilideacetate
Preparation Note
Working concentration: Approximately 0.2 mM
Storage conditions (working solution): 2 to 8 °C
A substrate solution (approx. 2 mM) is stable for at least 4 weeks if stored at 2 to 8 °C.
Storage conditions (working solution): 2 to 8 °C
A substrate solution (approx. 2 mM) is stable for at least 4 weeks if stored at 2 to 8 °C.
Other Notes
For life science research only. Not for use in diagnostic procedures.
Legal Information
Chromozym is a registered trademark of Pentapharm AG, Basel
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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E Perzborn et al.
Journal of thrombosis and haemostasis : JTH, 3(3), 514-521 (2005-03-08)
BAY 59-7939 is an oral, direct Factor Xa (FXa) inhibitor in development for the prevention and treatment of arterial and venous thrombosis. BAY 59-7939 competitively inhibits human FXa (K(i) 0.4 nm) with > 10 000-fold greater selectivity than for other
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