146072

N,N′-Methylenebis(acrylamide)

99%

• Synonym(s): Bis-acrylamide
• Linear Formula: (H₂C=CHCONH)₂CH₂
• CAS Number: 110-26-9
• Molecular Weight: 154.17
• EC Number: 203-750-9
• MDL number: MFCD00008625
• UNSPSC Code: 41105319
• PubChem Substance ID: 24848761
• Flavis number: 7.107
• NACRES: NB.22

Properties

• vapor density: 5.31 (vs air)
• Quality Level: 100
• Assay: 99%
• form: powder
• mp: >300 °C (lit.)
• solubility: water: soluble 20 g/L at 20 °C
• storage temp.: 2-8°C
• SMILES string: C=CC(=O)NCNC(=O)C=C
• InChI: 1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)
• InChI key: ZIUHHBKFKCYYJD-UHFFFAOYSA-N

Description

General description

N,N′-Methylenebis(acrylamide) is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel. It is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.

Application

N,N′-Methylenebis(acrylamide) has been used in gel preparation. It has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.

Cross-linking agent for preparation of polyacrylamides.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301 - H312 - H340 - H350 - H361fd - H372
• Precautionary Statements: P202 - P260 - P264 - P280 - P301 + P310 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Carc. 1B - Muta. 1B - Repr. 2 - STOT RE 1 Oral
• Target Organs: Peripheral nervous system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves