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F-907

Supelco

Flunitrazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H12FN3O3
CAS Number:
1622-62-4
Molecular Weight:
313.28
EC Number:
200-659-6
MDL number:
MFCD00057906
UNSPSC Code:
41116107
PubChem Substance ID:
329799782
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CN(C1=CC=C([N+]([O-])=O)C=C1C(C2=CC=CC=C2F)=NC3)C3=O

InChI

1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3

InChI key

PPTYJKAXVCCBDU-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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General description

A Certified Spiking Solution® suitable for use in GC/MS or LC/MS applications for clinical toxicology, forensic analysis, or urine drug testing. Flunitrazepam is an intermediate-acting benzodiazepine marketed under the trade name Rohypnol as a hypnotic, sedative, anticonvulsant and skeletal muscle relaxant.

Application


  • Flunitrazepam Detection in Biological Samples: This study discusses the use of Intralipid as a matrix additive for evaluating hyperlipidemic postmortem blood, where Flunitrazepam can be detected and quantified. This is critical for toxicological analysis, contributing to pharmacological and forensic science (Elenstål et al., 2023).

  • Electrochemical Detection of Flunitrazepam in Beverages: An innovative approach to the rapid detection of Flunitrazepam, commonly known as a ′date rape′ drug, in spirits using a screen-printed sensor. This method is crucial for public health and safety, providing a quick and effective way to test beverages for contamination (Papadopoulos et al., 2020).



Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Suzuki et al.
Endoscopy, 44(1), 38-42 (2011-12-07)
Studies have estimated that failure of cecal intubation occurs with conventional colonoscopy in up to 10 % of cases. Double-balloon endoscopy (DBE) systems, magnetic endoscope imaging (MEI), and transparent cap have been shown to improve success rates for colonoscopy. This study
J H Woods et al.
Journal of clinical psychopharmacology, 17(3 Suppl 2), 1S-57S (1997-06-01)
Flunitrazepam is among the most frequently prescribed hypnotics in many countries. Although it was never marketed in the United States, flunitrazepam, in recent years, has been smuggled into the country, and reports of abuse--including alleged use of the drug to
Vanessa Pauly et al.
International clinical psychopharmacology, 26(5), 268-277 (2011-08-11)
Fourteen benzodiazepine (BZD) or BZD-like medications were analyzed with three data sources aiming to assess prescription drug abuse for the year 2008. After a descriptive analysis, a principal component analysis was carried out to explore correlations between seven indicators obtained
Paul D'Aloise et al.
Science & justice : journal of the Forensic Science Society, 52(1), 2-8 (2012-02-14)
Desorption electrospray ionization-mass spectrometry (DESI-MS), a novel ambient ionization technique, was used in this study for determining flunitrazepam in various alcoholic beverages. Using this technique, no pretreatment of the samples was necessary and identification of the drug was accomplished in
M A Mattila et al.
Drugs, 20(5), 353-374 (1980-11-01)
Flunitrazepam is a benzodiazepine derivative whose hypnotic effect predominates over the sedative, anxiolytic, muscle-relaxing and anticonvulsant effects characteristic of benzodiazepines. Thus, it is used as a night-time hypnotic and in anaesthesiology: due to the pronounced hypnotic effect it is not
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