추천 제품
Grade
analytical standard
Quality Level
CofA
current certificate can be downloaded
포장
ampule of 1000 mg
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
clinical testing
형식
neat
저장 온도
2-30°C
SMILES string
CN(C)CCN(CC1=CC=CS1)C2=NC=CC=C2.Cl
InChI
1S/C14H19N3S.ClH/c1-16(2)9-10-17(12-13-6-5-11-18-13)14-7-3-4-8-15-14;/h3-8,11H,9-10,12H2,1-2H3;1H
InChI key
BONORRGKLJBGRV-UHFFFAOYSA-N
유전자 정보
human ... HRH1(3269)
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일반 설명
Methapyrilene is an H1-receptor antihistamine that is known to cause periportal hepatic necrosis following acute high dose administration to the rat subjects in in vitro studies carried out for the identification of mutagens and/or carcinogens.
애플리케이션
Methapyrilene HCl may be used as an analytical reference standard for the determination of the analyte in animal feed, human urine and wastewater by high-performance liquid chromatography (HPLC) and gas chromatography (GC) techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Trace analysis of the antihistamines methapyrilene hydrochloride, pyrilamine maleate and triprolidine hydrochloride monohydrate in animal feed, human urine and wastewater by high-performance liquid chromatography and gas chromatography with nitrogen-phosphorus detection.
Journal of Chromatography A, 283(3), 251-264 (1984)
Methapyrilene hepatotoxicity is associated with increased hepatic glutathione, the formation of glucuronide conjugates, and enterohepatic recirculation.
Chemico-Biological Interactions, 129(3), 279-295 (2000)
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