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Merck
모든 사진(1)

주요 문서

UC305

Sigma-Aldrich

O-Desmethylnaproxen

동의어(들):

(S)-6-Hydroxy-α-methyl-2-naphthaleneacetic acid, d-2-(6-Hydroxy-2-naphthyl)proprionic acid

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About This Item

실험식(Hill 표기법):
C13H12O3
CAS Number:
Molecular Weight:
216.23
Beilstein:
8838512
MDL number:
UNSPSC 코드:
12161501
PubChem Substance ID:
NACRES:
NA.77

양식

solid

Quality Level

색상

white

mp

182-183 °C

저장 온도

2-8°C

SMILES string

C[C@H](C(O)=O)c1ccc2cc(O)ccc2c1

InChI

1S/C13H12O3/c1-8(13(15)16)9-2-3-11-7-12(14)5-4-10(11)6-9/h2-8,14H,1H3,(H,15,16)/t8-/m0/s1

InChI key

XWJUDDGELKXYNO-QMMMGPOBSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

O-Desmethylnaproxen can be used for assaying naproxen metabolites.

생화학적/생리학적 작용

CYP2C9 metabolite of naproxen

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

픽토그램

Exclamation markEnvironment

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

C E Uboh et al.
Research communications in chemical pathology and pharmacology, 77(2), 201-218 (1992-08-01)
This study was undertaken to determine the applicability of plasma concentration of furosemide and specific gravity (SG) of urine in regulating the use of furosemide administered 4 hours prior to race time in Exercise-Induced Pulmonary Hemorrhage (EIPH) race horses. Nonbleeders
J V Andersen et al.
Journal of chromatography, 577(2), 325-333 (1992-06-10)
The glucuronides of the anti-inflammatory drug naproxen and its metabolite 6-O-desmethylnaproxen have been produced on a preparative scale by enzymatic synthesis. 6-O-Desmethylnaproxen, the glycine conjugate of naproxen and the O-sulphate of 6-O-desmethylnaproxen were prepared by chemical synthesis. Naproxen and the
T B Vree et al.
Journal of chromatography, 578(2), 239-249 (1992-07-24)
Naproxen is metabolized in humans by O-demethylation, and by acyl glucuronidation to the 1-O-glucuronide. Naproxen, its metabolite and the conjugates can be measured directly by gradient high-performance liquid chromatographic analysis without enzymic deglucuronidation. The glucuronide conjugates were isolated by preparative
Amitava Dasgupta et al.
American journal of clinical pathology, 133(6), 878-883 (2010-05-18)
A recent report indicated significant interference of naproxen with total bilirubin measurement when using the Jendrassik and Grof method. We explored the possibility of avoiding this interference by using a different method. We observed that naproxen has no effect on
Hypoalbuminaemia and naproxen pharmacokinetics in a patient with rheumatoid arthritis.
F A Van den Ouweland et al.
Clinical pharmacokinetics, 11(6), 511-515 (1986-11-01)

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