U0383

Umbelliferyl Arachidonate

ethanol solution

• 동의어(들): 5Z,8Z,11Z,14Z-Eicosatetraenoic acid 2-oxo-2H-1-benzopyran-7-yl ester, 7-Hydroxycoumarinyl Arachidonate
• 실험식(Hill 표기법): C₂₉H₃₆O₄
• CAS Number: 161180-11-6
• Molecular Weight: 448.59
• EC Number: 200-578-6
• MDL number: MFCD00797670
• UNSPSC 코드: 41106300
• PubChem Substance ID: 329827591
• NACRES: NA.32

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: ethanol solution
• 기술: immunofluorescence: suitable
• solubility: DMSO: soluble 25 mg/mL; DMF: soluble 50 mg/mL; aqueous buffer: slightly soluble
• 배송 상태: wet ice
• 저장 온도: −20°C
• SMILES string: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Oc1ccc2C=CC(=O)Oc2c1
• InChI: 1S/C29H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(30)32-26-22-20-25-21-23-29(31)33-27(25)24-26/h6-7,9-10,12-13,15-16,20-24H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-
• InChI key: SFTGFGOBCQCZDY-DOFZRALJSA-N

설명

애플리케이션

Umbelliferyl Arachidonate also known as 7-Hydroxycoumarinyl Arachidonate was used as a fluorogenic substrate for developing a fluorescence-based assay to evaluate the inhibitors against human recombinant monoacylglycerol lipase.

생화학적/생리학적 작용

Monoacylglycerol lipase (MAGL) protein facilitates the hydrolysis of Umbelliferyl Arachidonate and generates arachidonic acid and the highly fluorescent 7-hydroxyl coumarin (7-HC). Hence, it acts as a marker in a fluorescence-based assay.

제조 메모

Umbelliferyl Arachidonate can be dissolved in DMSO at 25 mg/ml and in DMF at 50 mg/ml. The product is sparingly soluble in aqueous buffers.

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H319
• 예방조치 성명서: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 57.2 °F - closed cup
• Flash Point (°C): 14 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter