T6069
Thio-TEPA
동의어(들):
N,N′,N″-Triethylenethiophosphoramide, Thio-Tep, Thiofozil, Thiotef, Tio-tef, Tiofosfamid, Tiofosyl, Tiofozil, Tris(aziridinyl)phosphine sulfide
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C6H12N3PS
CAS Number:
Molecular Weight:
189.22
EC Number:
MDL number:
UNSPSC 코드:
51102829
PubChem Substance ID:
NACRES:
NA.85
추천 제품
양식
solid
Quality Level
저장 조건
(Keep container tightly closed in a dry and well-ventilated place.)
색상
white
항생제 활성 스펙트럼
neoplastics
동작 모드
DNA synthesis | interferes
저장 온도
2-8°C
SMILES string
S=P(N1CC1)(N2CC2)N3CC3
InChI
1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2
InChI key
FOCVUCIESVLUNU-UHFFFAOYSA-N
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일반 설명
Chemical structure: aziridine
애플리케이션
A polyfunctional alkylating agent
생화학적/생리학적 작용
The unstable nitrogen-carbon groups alkylate with DNA which causes irreversible DNA damage. They stop tumor growth by crosslinking guanine nucleobases in DNA double-helix strands, directly attacking DNA. The DNA strands are unable to uncoil and separate which halts cell division.
분석 메모
Solubility - freely soluble in water , in chloroform and in ethanol (96%)
기타 정보
Keep container tightly closed in a dry and well-ventilated place.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Oral - Carc. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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