T4077

Anti-TAZ antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Taz Antibody, Taz Antibody - Anti-TAZ antibody produced in rabbit, Anti-Transcriptional co-activator with PDZ-binding motif
• MDL number: MFCD03792065
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen ~49 kDa
• 종 반응성: rat, human, mouse
• 기술: immunohistochemistry: suitable; western blot: 1:500-1:1,000
• UniProt 수납 번호: Q9GZV5
• 배송 상태: dry ice
• 저장 온도: −20°C
• 유전자 정보: human ... WWTR1(25937)

설명

일반 설명

Tafazzin (TAZ) is encoded by the WW domain containing transcription regulator 1 (WWTR1) gene mapped to human chromosome Xq28. The encoded protein contains 400 amino acids. It is characterized by a conserved WW domain, implicated in binding PPXY motif, a coiled-coil region associated with protein-protein interaction and a C-terminal motif involved in binding the PDZ domain.

면역원

synthetic peptide corresponding to residues 386-400 of human TAZ.

생화학적/생리학적 작용

Tafazzin (TAZ) plays a vital role in the various cellular process including cell proliferation, differentiation, apoptosis, migration, invasion, epithelial-mesenchymal transition (EMT) and stemness in multiple human cancers. TAZ associates with other transcription factors such as RUNX2 (runt-related transcription factor 2), PPAR (peroxisome proliferator-activated receptor), PAX3 and 8 (paired box gene 3 and 8) and TTF1 (thyroid transcription factor 1) and plays an essential role in osteoblastic, myogenic and adipogenic differentiation.

물리적 형태

solution in phosphate buffered saline, containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)