T2780

Monoclonal Anti-Tropomyosin antibody produced in mouse

clone TM311, ascites fluid

• 동의어(들): Anti-Tropomyosin Antibody
• MDL number: MFCD00149029
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: TM311, monoclonal
• 분자량: antigen 36-39 kDa
• 포함: 15 mM sodium azide
• 종 반응성: pig, chicken, bovine, rabbit, mouse, hamster, rat, human
• 기술: immunoprecipitation (IP): suitable; indirect ELISA: suitable; indirect immunofluorescence: 1:400 using chicken fibroblasts; microarray: suitable; western blot: suitable using human tissue and chicken gizzard extracts
• 동형: IgG1
• UniProt 수납 번호: P09493
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: bovine ... TPM1(281544) ; chicken ... TPM1(396366) ; human ... TPM1(7168) ; mouse ... Tpm1(22003) ; rat ... Tpm1(24851)

설명

일반 설명

Monoclonal Anti-Tropomyosin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Tropomyosin is a rigid rod-shaped protein closely associated with actin filaments. Non-muscle forms of tropomyosin have been identified in a wide range of cell types. Tropomyosin is made of two α helical polypeptide chains.

면역원

chicken gizzard tropomyosin.

애플리케이션

Monoclonal Anti-Tropomyosin has been used:

• in immunofluorescent labelling
• in immunohistochemistry
• in western blotting
• in immunoblotting

Mouse monoclonal clone TM311 anti-Tropomyosin antibody is used to tag tropomyosin for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. It is used as a probe to determine the presence and roles of tropomyosin in cytoskeletal structures.

생화학적/생리학적 작용

Tropomyosin together with troponin, regulate the binding of myosin to actin. Tropomyosin is a dimeric coiled-coil protein forming continuous polymers along the myosin-binding groove of actin. Various tropomyosin isoforms help to confer structure and function to actins in the cytoskeleton and in striated muscle function.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable