T0632

Sodium thioglycolate

≥96.5% (iodometric)

• 동의어(들): Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt
• Linear Formula: HSCH₂COONa
• CAS Number: 367-51-1
• Molecular Weight: 114.10
• Beilstein: 4569109
• EC Number: 206-696-4
• MDL number: MFCD00043386
• UNSPSC 코드: 12352201
• PubChem Substance ID: 24899901
• NACRES: NA.25

속성

• Quality Level: 200
• 분석: ≥96.5% (iodometric)
• 형태: powder
• 색상: white to off-white
• 유용한 pH 범위: 6.7 (20 °C, 100 g/L)
• mp: >300 °C (lit.)
• solubility: water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
• 저장 온도: −20°C
• SMILES string: [Na+].[O-]C(=O)CS
• InChI: 1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
• InChI key: GNBVPFITFYNRCN-UHFFFAOYSA-M

설명

애플리케이션

Sodium thioglycolate has been used:

• as a growth supplement in enrichment media and to study its effect on Arcobacter
• in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
• in electron microscopy

생화학적/생리학적 작용

Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

주의사항

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

기타 정보

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

안전성 정보

• 픽토그램: GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H290,H301,H312,H317,H412
• 예방조치 성명서: P234 - P261 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves