SRP6112

G6PD from E. coli

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 동의어(들): Glucose-6-phosphate 1-dehydrogenase, Zwf
• CAS Number: 9001-40-5
• UNSPSC 코드: 12352204
• NACRES: NA.32

속성

• 생물학적 소스: Escherichia coli
• 재조합: expressed in E. coli
• 분석: ≥90% (SDS-PAGE)
• 양식: liquid
• 분자량: 55.7 kDa (491 aa, 1-491 aa)
• 포장: pkg of 100 μg
• NCBI 수납 번호: P0AC53
• UniProt 수납 번호: P0AC53
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: Escherichia coli ... ZWF(7149716)

설명

일반 설명

Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH.

Specific activity is 8-10 units/ml obtained by measuring the increase of NADPH in absorbance at 340 nm resulting from the reduction of NAD or NADP.

생화학적/생리학적 작용

Glucose-6-phosphate dehydrogenase (G6PD) converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and simultaneously produces NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency causes acute hemolytic anemia.

물리적 형태

1 mg/mL solution in 50 mM MES pH 6.0, 0.1 mM PMSF, 2 mM EDTA, 0.5 mM DTT and 10% glycerol.

제조 메모

Centrifuge the vial prior to opening.

기타 정보

MAVTQTAQAC DLVIFGAKGD LARRKLLPSL YQLEKAGQLN PDTRIIGVGR ADWDKAAYTK VVREALETFM KETIDEGLWD TLSARLDFCN LDVNDTAAFS RLGAMLDQKN RITINYFAMP PSTFGAICKG LGEAKLNAKP ARVVMEKPLG TSLATSQEIN DQVGEYFEEC QVYRIDHYLG KETVLNLLAL RFANSLFVNN WDNRTIDHVE ITVAEEVGIE GRWGYFDKAG QMRDMIQNHL LQILCMIAMS PPSDLSADSI RDEKVKVLKS LRRIDRSNVR EKTVRGQYTA GFAQGKKVPG YLEEEGANKS SNTETFVAIR VDIDNWRWAG VPFYLRTGKR LPTKCSEVVV YFKTPELNLF KESWQDLPQN KLTIRLQPDE GVDIQVLNKV PGLDHKHNLQ ITKLDLSYSE TFNQTHLADA YERLLLETMR GIQALFVRRD EVEEAWKWVD SITEAWAMDN DAPKPYQAGT WGPVASVAMI TRDGRSWNEF E

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable