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Merck
모든 사진(2)

주요 문서

SRP5003

Sigma-Aldrich

AMPK (α2/β2/γ1), active, His tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

동의어(들):

AMPK, AMPK2, AMPKG, MGC61468, MGC8666, PRKAA, PRKAA2, PRKAB2, PRKAG1

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모든 사진(2)

About This Item

UNSPSC 코드:
12352202
NACRES:
NA.32

재조합

expressed in baculovirus infected Sf9 cells

제품 라인

PRECISIO® Kinase

분석

≥70% (SDS-PAGE)

양식

buffered aqueous glycerol solution

특이 활성도

238-322 nmol/min·mg

분자량

~36 kDa (B2)
 ~40 kDa (G1)
 ~69 kDa (A2)

NCBI 수납 번호

NM_002733
NM_005399
NM_006252

배송 상태

dry ice

저장 온도

−70°C

유전자 정보

human ... PRKAA2(5563) , PRKAB2(5565) , PRKAG1(5571)

일반 설명

AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis. AMPK exists as a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits. Binding of AMP to the γ subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKKβ.

물리적 형태

Supplied in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

제조 메모

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

법적 정보

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Danger

유해 및 위험 성명서

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
R100-2

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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Barbara B Kahn et al.
Cell metabolism, 1(1), 15-25 (2005-08-02)
The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular energy status, and recent data demonstrate that it also plays a critical role in systemic energy balance. AMPK integrates nutritional and hormonal signals in peripheral tissues and the
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Journal of cell science, 117(Pt 23), 5479-5487 (2004-10-29)
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