SRP4515

Artemin human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• 동의어(들): ART, ARTN, EVN, NBN
• MDL number: MFCD03099559
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥98% (SDS-PAGE)
• 형태: lyophilized
• 효능: 2-5 ng/mL ED₅₀ (it′s ability to stimulate the proliferation of human SH-SY5Y cells)
• 분자량: ~24 kDa
• 포장: pkg of 20 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: endotoxin, tested
• NCBI 수납 번호: NM_057090
• UniProt 수납 번호: Q5T4W7
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... ARTN(9048)

설명

일반 설명

Human Artemin, a neurotrophic factor, belongs to the GDNF family. Artemin is a survival factor for sensory and sympathetic neurons in culture. Recombinant human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits. The gene encoding this protein is localized on human chromosome 1p34.1.

생화학적/생리학적 작용

Artemin (ART/ARTN) is a survival factor for sensory and sympathetic neurons in culture. It has a role in promoting survival of neurons. ART is also involved in the differentiation and development of the central and peripheral nervous systems. The protein promotes axonal projection and migration in sympathetic neurons. Artemin restores neural damage and diminishes neuropathic pain. It has been associated with various carcinomas.

물리적 형태

Lyophilized from 10 mM Sodium Citrate pH 4.5 plus 150 mM NaCl.

제조 메모

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

재구성

Reconstitute in water to a concentration of 0.1-0.5 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Recontitute in PBS containing at least 0.1% BSA to a concentration of 0.1-1.0 mg/mL. This stock solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable