생물학적 소스
human
재조합
expressed in baculovirus infected Sf9 cells
분석
≥20% (SDS-PAGE)
양식
aqueous solution
분자량
90.5 kDa
포장
pkg of 50 μg
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
human ... TNFAIP3(7128)
일반 설명
Human A20, also known as tumor necrosis factor-α induced protein 3 (TNFAIP3) or OTU domain-containing protein 7C (OTUD7C), (GenBank Accession No. NM_006290) amino acids 2-791(end) with an N-terminal FLAG-tag, MW=90.5 kDa, expressed in Sf9 insect cells via a Baculovirus expression system.
애플리케이션
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Journal of biomedical science, 20, 74-74 (2013-10-09)
Intestinal polyps may further develop into colon cancer; the pathogenesis is not clear. The p53 gene is an important anti-cancer gene in the body, which is suppressed in cancer. The ubiquitin E3 ligase A20 (A20) plays a role in regulating
Autophagy, 6(7), 986-987 (2010-08-28)
Toll-like receptor 4 (TLR4) signaling triggers autophagy, which has been linked to both adaptive and innate immunity. Engagement of TLR4 recruits to the receptor complex Beclin 1, a key component of a class III phosphatidylinositol 3-kinase complex (PI3KC3) that initiates
Nature reviews. Cancer, 10(5), 332-341 (2010-04-13)
Clinicians have suspected for hundreds of years that chronic activation of the immune system contributes to the development of cancer. However, the molecular mechanisms that mediate this precarious interplay are only now being elucidated. Recent reports have identified A20 as
Immunity, 33(2), 181-191 (2010-08-14)
A20 is a ubiquitin modifying enzyme that restricts NF-kappaB signals and protects cells against tumor necrosis factor (TNF)-induced programmed cell death. Given recent data linking A20 (TNFAIP3) with human B cell lymphomas and systemic lupus erythematosus (SLE), we have generated
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