추천 제품
Quality Level
분석
≥98% (HPLC)
양식
oil
색상
colorless to yellow
저장 온도
2-8°C
SMILES string
O=S(C)CCCCCCN=C=S
InChI
1S/C8H15NOS2/c1-12(10)7-5-3-2-4-6-9-8-11/h2-7H2,1H3
InChI key
XQZVZULJKVALRI-UHFFFAOYSA-N
생화학적/생리학적 작용
6-(Methylsulfinyl)hexyl isothiocyanate (6-MITC) is a major bioactive compound in wasabi that exhibits antimicrobial, anti-inflammatory, antiplatelet, antioxidant and anticancer properties (mean log GI50 = −5.41 (3.9 μM) in a human cancer cell panel). 6-MITC concurrently induces autophagy and mitotic arrest, suppresses NF-κβ signaling by competitive inhibition of GSK-3β.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) from Wasabia japonica alleviates inflammatory bowel disease (IBD) by potential inhibition of glycogen synthase kinase 3 beta (GSK-3?)
Lohning A, Kidachi Y, Kamiie K, Sasaki K, Ryoyama K, Yamaguchi H
European Journal of Medicinal Chemistry, 216 (2021)
Akira Uruno et al.
Molecular and cellular biology, 40(6) (2020-01-15)
Nrf2 (NF-E2-related-factor 2) is a stress-responsive transcription factor that protects cells against oxidative stresses. To clarify whether Nrf2 prevents Alzheimer's disease (AD), AD model AppNL-G-F/NL-G-F knock-in (AppNLGF ) mice were studied in combination with genetic Nrf2 induction model Keap1FA/FA mice.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.