SML3542

SGC-UBD253

≥98% (HPLC)

• 동의어(들): 3-(8-Chloro-3-(2-(2-methoxybenzylamino)-2-oxoethyl)-4-oxo-3,4-dihydroquinazolin-2-yl)propanoic acid
• 실험식(Hill 표기법): C₂₁H₂₀ClN₃O₅
• Molecular Weight: 429.85
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• 저장 온도: 2-8°C
• SMILES string: O=C(NCC(C=CC=C1)=C1OC)CN(C(CCC(O)=O)=N2)C(C3=C2C(Cl)=CC=C3)=O

설명

생화학적/생리학적 작용

SGC-UBD253 is a cell penetrant, potent and selective chemical probe for the ubiquitin binding domain (UBD) of HDAC6 (histone deacetylase 6). SGC-UBD253 potently binds to HDAC6 UBD (KD = 84 nM) and inhibits the HDAC6-ISG15 interaction (EC50 = 1.9 µM).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable