SML3507
Hirsutine
≥98% (HPLC)
동의어(들):
(αE,2S,3R,12bR)-3-Ethyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic acid methyl ester, (E)-16,17-Didehydro-17-methoxy-17,18-seco-3-beta-yohimban-16-carboxylic acid methyl ester
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C22H28N2O3
CAS Number:
Molecular Weight:
368.47
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
-10 to -25°C
SMILES string
CC[C@@]1([H])CN(CCC2=C3NC4=C2C=CC=C4)[C@]3([H])C[C@]1([H])/C(C(OC)=O)=C\OC
InChI
1S/C22H28N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h5-8,13-14,17,20,23H,4,9-12H2,1-3H3/b18-13+/t14-,17-,20+/m0/s1
InChI key
NMLUOJBSAYAYEM-AZQGJTAVSA-N
생화학적/생리학적 작용
Hirsutine is a brain penetrant alkaloid from Uncaria rhynchophylla that exhibit anti-cancer, cardioprotective, anti-hypertensive, and anti-arrhythmic activities. It appears that hirsutine induces apoptosis in lung cancer cells through opening of mitochondrial permeability transition pore (mPTP). Hirsutine exhibit potent anti-dengue virus activity.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Rong Zhang et al.
Cell death & disease, 9(6), 598-598 (2018-05-24)
Hirsutine extracted from Uncaria rhynchophylla has been shown to exhibit anti-cancer activity. However, the molecular mechanism by which hirsutine exhibits anti-lung cancer activity remains unclear. In the present study, we showed that hirsutine induces apoptosis in human lung cancer cells
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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