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Merck
모든 사진(1)

주요 문서

SML3271

Sigma-Aldrich

Etoricoxib

≥95% (HPLC)

동의어(들):

5-Chloro-3-[4-(methylsulfonyl)phenyl]-2-(2-methyl-5-pyridinyl)pyridine, 5-Chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine

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About This Item

실험식(Hill 표기법):
C18H15ClN2O2S
CAS Number:
Molecular Weight:
358.84
Beilstein:
8073797
MDL number:
UNSPSC 코드:
12352107
NACRES:
NA.77

Quality Level

분석

≥95% (HPLC)

형태

powder

색상

white to beige

solubility

DMSO: 2 mg/mL, clear

저장 온도

2-8°C

SMILES string

CC1=NC=C(C2=C(C3=CC=C(S(C)(=O)=O)C=C3)C=C(Cl)C=N2)C=C1

InChI

1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3

InChI key

MNJVRJDLRVPLFE-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 4 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Lalita Tanwar et al.
Asian Pacific journal of cancer prevention : APJCP, 11(5), 1329-1333 (2011-01-05)
In the present study, we assessed effects of etoricoxib, a non-steroidal anti-inflammatory drug, on proliferation and apoptosis in 1,2-dimethylhydrazine dihydrochloride (DMH) induced colon lesion development. Male SD rats were divided into four groups: Group 1 controls receiving the vehicle treatment;
D Riendeau et al.
The Journal of pharmacology and experimental therapeutics, 296(2), 558-566 (2001-02-13)
We report here the preclinical profile of etoricoxib (MK-0663) [5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl) pyridine], a novel orally active agent that selectively inhibits cyclooxygenase-2 (COX-2), that has been developed for high selectivity in vitro using whole blood assays and sensitive COX-1 enzyme assays at
Sebastián A Cuesta et al.
Molecules (Basel, Switzerland), 26(13) (2021-07-20)
In this review, a timeline starting at the willow bark and ending in the latest discoveries of analgesic and anti-inflammatory drugs will be discussed. Furthermore, the chemical features of the different small organic molecules that have been used in pain

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