SML3208

CPYPP

≥98% (HPLC)

• 동의어(들): 4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
• 실험식(Hill 표기법): C₁₈H₁₃ClN₂O₂
• CAS Number: 310460-39-0
• Molecular Weight: 324.76
• MDL number: MFCD00980987
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: orange to dark red
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
• InChI: 1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)

설명

생화학적/생리학적 작용

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.

안전성 정보

• Storage Class Code: 11 - Combustible Solids