SML3082

Demethylwedelolactone

≥98% (HPLC)

• 동의어(들): 1,3,8,9-Tetrahydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one, 1,3,8,9-Tetrahydroxy-6H-benzofuro[3,2-c]chromen-6-one; 1,3,8,9-Tetrahydroxycoumestan, Desmethylwedelolactone, Norwedelolactone
• 실험식(Hill 표기법): C₁₅H₈O₇
• CAS Number: 6468-55-9
• Molecular Weight: 300.22
• MDL number: MFCD09264645
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to green
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: O=C1OC2=C(C(O)=CC(O)=C2)C3=C1C4=C(O3)C=C(O)C(O)=C4
• InChI: 1S/C15H8O7/c16-5-1-9(19)13-11(2-5)22-15(20)12-6-3-7(17)8(18)4-10(6)21-14(12)13/h1-4,16-19H
• InChI key: LUTYTNLPIUCKBJ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Demethylwedelolactone is a coumestan extracted from Eclipta alba that exhibits numerous biological activities including anti-inflammatory and hepato-protective. Demethylwedelolactone inhibits MDA-MB-231 breast cancer cells motility and invasiveness. It suppresses the metastasis and lung colonization of the tumor cells in the nude mice. Both demethylwedelolactone and wedelolactone appear to attenuate cigarette smoking extract induced inflammation through blockade of autophagy flux in respiratory epithelial cells.

coumestan extracted from Eclipta alba that exhibits numerous biological activities including anti-inflammatory and hepato-protective

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable