SML2964

Gabexate mesylate

≥97% (HPLC)

• 동의어(들): Gabexate mesylate, 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate, FOY, p-Carbethoxyphenyl ε-guanidineocaproate mesylate, 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxyl]benzoic acid ethyl ester mesylate salt, Megacart
• 실험식(Hill 표기법): C₁₆H₂₃N₃O₄ · CH₄O₃S
• CAS Number: 56974-61-9
• Molecular Weight: 417.48
• MDL number: MFCD00210299
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CS(O)(=O)=O.CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1
• InChI: 1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
• InChI key: DNTNDFLIKUKKOC-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Gabexate mesylate is a competitive inhibitor of serine proteases that displays high selectivity for TMPRSS2 (Transmembrane protease serine 2) (IC50 = 130 nM) with little or no activity towards several MMPs, caspases and USPs (>> 10 μM). Gabexate mesylate was reported to decrease inflammatory cytokines production and be useful as an anticoagulant.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable