SML2751

UCSF7447

≥98% (HPLC)

• 동의어(들): 2-Bromo-4-chloro-N-[3-(1H-1,2,4-triazol-5-yl)phenyl]-benzenemethanamine, ZINC555417447
• 실험식(Hill 표기법): C₁₅H₁₂BrClN₄
• CAS Number: 2305480-97-9
• Molecular Weight: 363.64
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: Brc1c(ccc(c1)Cl)CNc2cc(ccc2)c3[nH]ncn3
• InChI: 1S/C15H12BrClN4/c16-14-7-12(17)5-4-11(14)8-18-13-3-1-2-10(6-13)15-19-9-20-21-15/h1-7,9,18H,8H2,(H,19,20,21)
• InChI key: QPTCYEYTAWEZNT-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

UCSF7447 (ZINC555417447) brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor, which decelerates re-entrainment in mouse model of east-bound jetlag. Unexpectedly UCSF7447 advances the phase of the mouse circadian clock when administer at dusk.

brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable