추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to very dark brown
solubility
DMSO: 2 mg/mL, clear (warmed)
저장 온도
2-8°C
SMILES string
Fc1c(cccc1)C[n]2nc(c5c2nccc5)c3nc(c(c(n3)N)N4CCOCC4)N
InChI
1S/C21H21FN8O/c22-15-6-2-1-4-13(15)12-30-21-14(5-3-7-25-21)16(28-30)20-26-18(23)17(19(24)27-20)29-8-10-31-11-9-29/h1-7H,8-12H2,(H4,23,24,26,27)
InChI key
AQYFUZRYBJBAGZ-UHFFFAOYSA-N
생화학적/생리학적 작용
BAY 41-8543 is a stimulator of soluble Guanylyl cyclase (guanylate cyclase, sGC), the primary cellular receptor for nitric oxide (NO).
Guanylyl cyclase (sGC) stimulator
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
A Cervantes et al.
Cancer letters, 41(2), 169-177 (1988-08-15)
The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin (Dox) was studied in a Dox sensitive human ovarian cancer cell line (A2780) and its multidrug resistant counterpart (2780AD) using reactive oxygen scavengers. In both cell lines, a significant
Karin P Potoka et al.
American journal of respiratory cell and molecular biology, 58(5), 636-647 (2017-12-22)
Sickle cell disease (SCD) is associated with intravascular hemolysis and oxidative inhibition of nitric oxide (NO) signaling. BAY 54-6544 is a small-molecule activator of oxidized soluble guanylate cyclase (sGC), which, unlike endogenous NO and the sGC stimulator, BAY 41-8543, preferentially
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