SML2654
Telaprevir
≥90% (HPLC)
동의어(들):
2-(2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-(1-(cyclopropylamino)-1,2-dioxohexan-3-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide, LY-570310, VX-950
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C36H53N7O6
Molecular Weight:
679.85
MDL number:
UNSPSC 코드:
12352107
NACRES:
NA.77
추천 제품
분석
≥90% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
−20°C
SMILES string
[H][C@@]1([C@@]2(CCC1)[H])CN(C([C@@H](NC([C@@H](NC(C3=NC=CN=C3)=O)C4CCCCC4)=O)C(C)(C)C)=O)[C@@H]2C(N[C@H](C(C(NC5CC5)=O)=O)CCC)=O
InChI key
BBAWEDCPNXPBQM-GDEBMMAJSA-N
생화학적/생리학적 작용
Potent HCV NS3/4A protease inhibitor
Telaprevir is a potent, selective and orally active hepatitis C virus (HCV) NS3.4A serine protease inhibitor. Telaprevir also inhibits chymotrypsin, chymase, elastase, and cathepsins F, K, L, S, and V in vitro
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Repr. 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Robert B Perni et al.
Antimicrobial agents and chemotherapy, 50(3), 899-909 (2006-02-24)
VX-950 is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease, and it demonstrated excellent antiviral activity both in genotype 1b HCV replicon cells (50% inhibitory concentration [IC50] = 354 nM) and in human fetal
Gema Méndez-Lagares et al.
Journal of immunology (Baltimore, Md. : 1950), 200(3), 1124-1132 (2017-12-22)
The contribution of the host immune system to the efficacy of new anti-hepatitis C virus (HCV) drugs is unclear. We undertook a longitudinal prospective study of 33 individuals with chronic HCV treated with combination pegylated IFN-α, ribavirin, and telaprevir/boceprevir. We
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