모든 사진(1)
About This Item
실험식(Hill 표기법):
C14H11NO4
CAS Number:
Molecular Weight:
257.24
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
색상
yellow to orange
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
OC1=C(C=C(C=C1C=O)CC2=CC=CC=C2)[N+]([O-])=O
생화학적/생리학적 작용
Col003 is a cell penetrant, selective and potent inhibitor of the interaction of Hsp47 with collagen. It binds to the collagen binding site on Hsp47. Col003 inhibits a collagen secretion by destabilization the collagen triple helix. Additionally Col003 weakly inhibits interaction of collagen with prolyl 4-hydroxylase (P4H).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Shinya Ito et al.
The Journal of biological chemistry, 292(49), 20076-20085 (2017-10-14)
Fibrosis can disrupt tissue structure and integrity and impair organ function. Fibrosis is characterized by abnormal collagen accumulation in the extracellular matrix. Pharmacological inhibition of collagen secretion therefore represents a promising strategy for the management of fibrotic disorders, such as
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