SML2262

Ramelteon

• 동의어(들): Ramelteon solution, (S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide, N-[2-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide, TAK 375, TAK-375
• 실험식(Hill 표기법): C₁₆H₂₁NO₂
• CAS Number: 196597-26-9
• Molecular Weight: 259.34
• MDL number: MFCD08067736
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 형태: powder
• 광학 활성: [α]/D -50 to -60°, c = 1.0 in chloroform-d
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CCC(NCC[C@H]1C(C(CCO2)=C2C=C3)=C3CC1)=O
• InChI: 1S/C16H21NO2/c1-2-15(18)17-9-7-12-4-3-11-5-6-14-13(16(11)12)8-10-19-14/h5-6,12H,2-4,7-10H2,1H3,(H,17,18)/t12-/m0/s1
• InChI key: YLXDSYKOBKBWJQ-LBPRGKRZSA-N
• 유전자 정보: human ... MTNR1A(4543) , MTNR1B(4544)

설명

생화학적/생리학적 작용

Ramelteon is a cell penetrant, potent and selective agonist at MT1/MT2 melatonin receptor that exhibits sleep-promoting properties. It is not binding to GABA receptor complex. Ramelteon is an analog of melatonin recently approved to treat insomnia.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable