추천 제품
분석
≥95% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
저장 온도
−20°C
InChI
1S/C20H19FN4O4/c21-14-5-11-17(25(10-1-2-10)7-13(19(11)26)20(27)28)12(6-22)18(14)24-8-15-16(9-24)29-4-3-23-15/h5,7,10,15-16,23H,1-4,8-9H2,(H,27,28)/t15-,16-/m0/s1
InChI key
FYMHQCNFKNMJAV-HOTGVXAUSA-N
생화학적/생리학적 작용
Finafloxacin is a fluoroquinolone antibiotic approved by the FDA in 2014 for treating swimmer′s ear. Its mechanism of action involves the inhibition of bacterial type II topoisomerase enzymes, DNA gyrase and topoisomerase IV
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Muta. 1B - Repr. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Will Stubbings et al.
Antimicrobial agents and chemotherapy, 55(9), 4394-4397 (2011-06-29)
Finafloxacin is a novel fluoroquinolone that exhibits enhanced antibacterial activity under acidic conditions. The aim of this study was to define the in vitro pH-activity relationship. Finafloxacin exhibited optimal antibacterial activity between pH 5.0 and 6.0 at which MICs were
Jung Won Lee et al.
Antimicrobial agents and chemotherapy, 59(12), 7629-7636 (2015-09-30)
Finafloxacin is a novel fluoroquinolone with improved antimicrobial efficacy, especially in an acidic environment. The efficacy of finafloxacin for the inhibition of Helicobacter pylori infection was compared with the efficacies of levofloxacin and moxifloxacin at neutral and acidic pH. The
Finafloxacin overcomes Burkholderia pseudomallei efflux-mediated fluoroquinolone resistance.
Linnell B Randall et al.
The Journal of antimicrobial chemotherapy, 72(4), 1258-1260 (2017-01-01)
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