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Merck
모든 사진(1)

Key Documents

SML1807

Sigma-Aldrich

SB-258719

≥98% (HPLC)

동의어(들):

N,3-Dimethyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]benzenesulfonamide, SB 258719

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About This Item

실험식(Hill 표기법):
C18H30N2O2S
CAS Number:
Molecular Weight:
338.51
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

형태

oil

색상

off-white to brown

저장 온도

2-8°C

SMILES string

CC1=CC=CC(S(N(C)[C@H](C)CCN2CCC(C)CC2)(=O)=O)=C1

InChI

1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3

InChI key

AGVNHDNTFYHZNL-UHFFFAOYSA-N

생화학적/생리학적 작용

SB-258719 is a selective and potent 5-HT7 antagonist. SB-258719 reverses the hypothermic effect of 5-CT in mice.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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D R Thomas et al.
British journal of pharmacology, 124(6), 1300-1306 (1998-08-28)
1. The functional profile of the long form of the human cloned 5-HT7 receptor (designated h5-HT7(a)) was investigated using a number of 5-HT receptor agonists and antagonists and compared with its binding profile. Receptor function was measured using adenylyl cyclase
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