SML1623

MSP-3

≥98% (HPLC)

• 동의어(들): N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide
• 실험식(Hill 표기법): C₁₆H₁₉NO₃S
• CAS Number: 1820968-63-5
• Molecular Weight: 305.39
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825508
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: oil
• 색상: white to beige
• 저장 온도: room temp
• SMILES string: O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
• InChI: 1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
• InChI key: HCUVEUVIUAJXRB-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable