SML1537

Cantharidin Ready Made Solution

0.1 mg/mL in DMSO

• 동의어(들): 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• 실험식(Hill 표기법): C₁₀H₁₂O₄
• CAS Number: 56-25-7
• Molecular Weight: 196.20
• EC Number: 200-664-3
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 생물학적 소스: insect
• Quality Level: 200
• 양식: solution
• 농도: 0.1 mg/mL in DMSO
• 배송 상태: ambient
• 저장 온도: 2-8°C
• SMILES string: O1[C@@H]2[C@]3([C@@]([C@H]1CC2)(C(=O)OC3=O)C)C
• InChI: 1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
• InChI key: DHZBEENLJMYSHQ-XCVPVQRUSA-N

설명

생화학적/생리학적 작용

Cantharidin inhibits protein phosphatase 2A.

It is a component of mylabris, a traditional Chinese medicine. Cantharidin exhibits anti-tumor activity. In addition, cantharidin can work against multidrug-resistant cells. In the epidermis, it causes release of neutral serine proteases, leading to degeneration of the desmosmal plaque. This results in acantholysis and intraepidermal blistering as well as skin lysis. PP2A is involved in the cell cycle, cell death, growth and cell-fate determination.

기타 정보

Stable for at least two years at 2-8° C.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 188.6 °F
• Flash Point (°C): 87 °C