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Merck
모든 사진(1)

주요 문서

SML1023

Sigma-Aldrich

Flucloxacillin sodium

≥95% (HPLC)

동의어(들):

(2S,5R,6R)-6-[[[3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium, BRL 2039 sodium, FK 900 sodium, Floxacillin sodium

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About This Item

실험식(Hill 표기법):
C19H16ClFN3O5S · Na
CAS Number:
Molecular Weight:
475.85
EC Number:
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥95% (HPLC)

양식

powder

저장 조건

protect from light

색상

white to beige

solubility

H2O: 20 mg/mL, clear

저장 온도

−20°C

SMILES string

[Na+].Fc1c(c(ccc1)Cl)c2n[o]c(c2\C(=N\[C@H]3[C@H]4SC([C@@H](N4C3=O)C(=O)O)(C)C)\[O-])C

InChI

1S/C19H17ClFN3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/q;+1/p-1/t13-,14+,17-;/m1./s1

InChI key

OTEANHMVDHZOPB-SLINCCQESA-M

일반 설명

Flucloxacillin sodium, a sodium salt of flucloxacillin, is a member of the penicillin class.

애플리케이션

Flucloxacillin sodium has been used as a β-lactam antibiotic to study its effects on methicillin-resistant Staphylococcus aureus (MRSA) ΔfloA mutant.

생화학적/생리학적 작용

Flucloxacillin exhibits antimicrobial property.
Flucloxacillin is a narrow-spectrum β-lactam antibiotic used to treat Gram-positive bacterial infections. Flucloxacillin induces cholestatic liver damage.
Flucloxacillin is a narrow-spectrum β-lactam antibiotic.

기타 정보

Light sensitive

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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이미 열람한 고객

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Handbook of Pharmaceutical Excipients (2014)
Apparent Molar Volume, Adiabatic Compressibility, and Critical Micelle Concentration of Flucloxacillin Sodium in Aqueous NaCl Solutions at Different Temperatures
Khatun MR, et al.
Journal of Chemical and Engineering Data, 61(1), 102-113 (2016)
Esther García-Fernández et al.
Cell, 171(6), 1354-1367 (2017-11-07)
A number of bacterial cell processes are confined functional membrane microdomains (FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells. How bacteria organize these intricate platforms and what their biological significance is remain important questions. Using the pathogen
Ryan Nattrass et al.
Toxicological sciences : an official journal of the Society of Toxicology, 146(1), 146-156 (2015-04-17)
There are currently no animal models of drug-induced liver injury (DILI) where the adaptive immune system has been shown to damage the liver. Thus, it is difficult to explore the mechanistic basis of the tissue injury. The aim of this

관련 콘텐츠

We offer agonists, antagonists, modulators and other bioactive small molecules for immune system signaling target identification and validation, as well as a variety of antibiotics, antivirals, and antifungals.

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