SML0874

GMQ hydrochloride

≥95% (HPLC)

• 동의어(들): 2-Guanidine-4-methylquinazoline hydrochloride, 4-Methyl-2-guanidino quinazoline hydrochloride, N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride, NSC 403387 hydrochloride
• 실험식(Hill 표기법): C₁₀H₁₁N₅ · HCl
• CAS Number: 5361-15-9
• Molecular Weight: 237.69
• MDL number: MFCD00035249
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825612
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• 저장 온도: room temp
• SMILES string: CC1=NC(NC(N)=N)=NC2=C1C=CC=C2.Cl
• InChI: 1S/C10H11N5.ClH/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12;/h2-5H,1H3,(H4,11,12,13,14,15);1H
• InChI key: VNPZWQRWOHFAPD-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

GMQ/2-Guanidine-4-methylquinazoline is a potent and selective modulator of acid-sensing ion channel (ASIC) that activates ASIC3 channels under neutral pH. GQM blocks acid-induced maximal peak current and alters ASICs pH dependence for activation and inactivation.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable