SML0858

SC-1

≥98% (HPLC)

• 동의어(들): N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(4-cyanophenoxy)phenyl]-urea
• 실험식(Hill 표기법): C₂₁H₁₃ClF₃N₃O₂
• CAS Number: 1313019-65-6
• Molecular Weight: 431.80
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 15 mg/mL, clear
• 저장 온도: 2-8°C

설명

생화학적/생리학적 작용

SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib with no kinase-inhibition activity. SC-1 blocks STAT3 phosphorylation and activation with similar potency to sorafenib, and induces apoptosis in hepatocellular carcinoma cell lines.

SC-1 is an inhibitor of STAT3 signaling pathway.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319,H413
• 예방조치 성명서: P264 - P273 - P280 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Aquatic Chronic 4 - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable