SML0672

VU0405601

≥98% (HPLC)

• 동의어(들): 2-[(1-Bromo-2-naphthalenyl)oxy]-N-3-pyridinyl-acetamide
• 실험식(Hill 표기법): C₁₇H₁₃BrN₂O₂
• CAS Number: 712325-30-9
• Molecular Weight: 357.20
• MDL number: MFCD05995040
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825580
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: BrC1=C2C=CC=CC2=CC=C1OCC(NC3=CC=CN=C3)=O
• InChI: 1S/C17H13BrN2O2/c18-17-14-6-2-1-4-12(14)7-8-15(17)22-11-16(21)20-13-5-3-9-19-10-13/h1-10H,11H2,(H,20,21)
• InChI key: WLLRAGBPCSOJNH-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

VU0405601 is a hERG (the human Ether-à-go-go-Related Gene) agonist that increased the IC₅₀ of dofetilide from 38.7 nM to 76.3 nM. VU0405601 protects against arrhythmias induced by hERG inhibition.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302 - H315 - H319 - H335
• 예방조치 성명서: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable