SML0574
YM-298198 hydrochloride
≥98% (HPLC)
동의어(들):
6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H22N4OS · HCl
CAS Number:
Molecular Weight:
378.92
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
저장 조건
desiccated
색상
white to beige
solubility
H2O: 5 mg/mL, clear
저장 온도
2-8°C
SMILES string
Cl.CN(C1CCCCC1)C(=O)c2sc3nc4ccc(N)cc4n3c2C
InChI
1S/C18H22N4OS.ClH/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18;/h8-10,13H,3-7,19H2,1-2H3;1H
InChI key
WYTJVUVCSUWZTH-UHFFFAOYSA-N
생화학적/생리학적 작용
YM-298198 is an orally active, noncompetitive mGlu1 receptor antagonist. The compound inhibits glutamate-induced inositol phosphate production in NIH3T3 cells (IC50 = 16 nM). YM-298198 displays analgesic and antinociceptive properties in vivo.
특징 및 장점
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Haein Weon et al.
Life sciences, 188, 110-117 (2017-09-09)
Both N-type and P/Q-type voltage-gated Ca (S)-3,5-Dihydroxyphenylglycine (DHPG; 10μM for 5min), the group I mGluR agonist, was used to induce LTP of excitatory postsynaptic currents that were evoked in the Vo neurons by stimulating the trigeminal track. Weak blockade of
문서
Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.
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