SML0574

YM-298198 hydrochloride

≥98% (HPLC)

• 동의어(들): 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride
• 실험식(Hill 표기법): C₁₈H₂₂N₄OS · HCl
• CAS Number: 1216398-09-2
• Molecular Weight: 378.92
• MDL number: MFCD08703122
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825561
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 5 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: Cl.CN(C1CCCCC1)C(=O)c2sc3nc4ccc(N)cc4n3c2C
• InChI: 1S/C18H22N4OS.ClH/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18;/h8-10,13H,3-7,19H2,1-2H3;1H
• InChI key: WYTJVUVCSUWZTH-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

YM-298198 is a selective, noncompetitive mGlu1 receptor antagonist.

YM-298198 is an orally active, noncompetitive mGlu1 receptor antagonist. The compound inhibits glutamate-induced inositol phosphate production in NIH3T3 cells (IC₅₀ = 16 nM). YM-298198 displays analgesic and antinociceptive properties in vivo.

특징 및 장점

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable