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Merck
모든 사진(1)

Key Documents

SML0351

Sigma-Aldrich

CPDT

≥96% (HPLC)

동의어(들):

5,6-Dihydro-Cyclopenta[c]-1,2-dithiole-3(4H)-thione, CJ 11788, SNU2A

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About This Item

실험식(Hill 표기법):
C6H6S3
CAS Number:
Molecular Weight:
174.31
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

분석

≥96% (HPLC)

형태

powder

색상

faintly red to very dark red

solubility

DMSO: 2 mg/mL (warmed)

저장 온도

2-8°C

SMILES string

S=C1SSC2=C1CCC2

InChI

1S/C6H6S3/c7-6-4-2-1-3-5(4)8-9-6/h1-3H2

InChI key

AVSGTGUIBQOXJK-UHFFFAOYSA-N

애플리케이션

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) has been used to study its protective effects and the underlying mechanism in diabetic cardiomyopathy.

생화학적/생리학적 작용

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) is a phase II enzyme inducer. It exhibits protective actions against chemical carcinogens.
CPTD (SNU2A) is a cytoprotective agent that protects mitochondria during cell stress by increasing antioxidant capacity. CPTD inhibits phosphorylation and activation of Fyn, which maintains AMPK activity and activation of Nrf2.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Ying Miao et al.
BioMed research international, 2017, 9167450-9167450 (2018-02-07)
Diabetic cardiomyopathy (DCM) is a common heart disease. The Phase II enzyme inducer (CPDT) is a complex enzyme that promotes the expression of antioxidant enzymes through activating nuclear factor erythroid 2-related factor 2 (Nrf2); these compounds have been shown to
Wenyan Guo et al.
International journal of biological macromolecules, 135, 619-629 (2019-05-28)
The aim of this study was to investigate the effects of biomacromolecules mannan/β-glucans from yeast cell wall (BYCW) to alleviate Deoxynivalenol(DON)-induced injury. Considering that DON has strong oxidizing effect and stimulates autophagy and apoptosis, we examined the effects of BYCW
Matías Regiart et al.
Analytica chimica acta, 963, 83-92 (2017-03-25)
We report a hybrid glass-poly (dimethylsiloxane) microfluidic immunosensor for epidermal growth factor receptor (EGFR) determination, based on the covalent immobilization of anti-EGFR antibody (anti-EGFR) on amino-functionalized mesoporous silica (AMS) retained in the central channel of a microfluidic device. The synthetized
Liqin Mei et al.
Journal of materials chemistry. B, 8(25), 5434-5440 (2020-06-13)
Zwitterionic polymers have attracted increasing attention due to their excellent fouling resistance ability and eco-friendliness. Yet, their non-degradability and hydrophilic nature limit their applications. In this study, we have prepared a novel surface-fragmenting hyperbranched copolymer with tertiary carboxybetaine ester (TCB)
Hsiu-Pen Lin et al.
Macromolecular bioscience, 20(6), e2000049-e2000049 (2020-04-08)
Cationic polymers exhibit high cytotoxicity via strong interaction with cell membranes. To reduce cell membrane damage, a hydrophilic polymer is introduced to the cationic nanoparticle surface. The hydrophilic polymer coating of cationic nanoparticles resulted in a nearly neutral nanoparticle. These

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